mouse API5 Over-expression AAV

Name 
AAV-m-API5
Cat No 
AAV-278554
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Api5.

AAV-278554
AAV-m-API5

Ready-to-use AAV expressing Mouse Api5 (apoptosis inhibitor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AAC-11; AI196452; API-5
Description (Vector)
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Gene ID
11800
Gene Name (Vector)
apoptosis inhibitor 5
Gene Symbol
Api5
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_007466
RefSeq Synonyms
NM_007466, NM_001305258, BC007133,
Species
mouse
UniGene ID
Mm.181824

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.