mouse UGT1A1 Over-expression AAV

Name
AAV-m-UGT1A1

Cat No
AAV-278232

Availability
4-5 weeks

This is an AAV expressing Mouse Ugt1a1.

AAV-278232

AAV-m-UGT1A1

Ready-to-use AAV expressing Mouse Ugt1a1 (UDP glucuronosyltransferase 1 family, polypeptide A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Gnt1; UDPGT 1-1; Udpgt-1a; UGT1A01; UgtBr1

Description (Vector)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.

Gene ID

394436

Gene Name (Vector)

UDP glucuronosyltransferase 1 family, polypeptide A1

Gene Symbol

Ugt1a1

ORF Size (aa)

1608

ORF Size (bp)

1608 bp

RefSeq ID

NM_201645

RefSeq Synonyms

NM_201645, BC093516,

Species

mouse

UniGene ID

Mm.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.