mouse ZIC1 Over-expression AAV

Name
AAV-m-ZIC1

Cat No
AAV-277062

Availability
4-5 weeks

This is an AAV expressing Mouse Zic1.

AAV-277062

AAV-m-ZIC1

Ready-to-use AAV expressing Mouse Zic1 (zinc finger protein of the cerebellum 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ZIC; ZNF201

Description (Vector)

Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).

Gene ID

22771

Gene Name (Vector)

zinc finger protein of the cerebellum 1

Gene Symbol

Zic1

ORF Size (aa)

1344

ORF Size (bp)

1344 bp

RefSeq ID

NM_009573

RefSeq Synonyms

NM_009573, BC063247, BC060247, BC050889,

Species

mouse

UniGene ID

Mm.477226

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.