mouse WT1 Over-expression AAV

Name 
AAV-m-WT1
Cat No 
AAV-276348
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Wt1.

AAV-276348
AAV-m-WT1

Ready-to-use AAV expressing Mouse Wt1 (Wilms tumor 1 homolog). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D630046I19Rik; Wt-1
Description (Vector)
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Gene ID
22431
Gene Name (Vector)
Wilms tumor 1 homolog
Gene Symbol
Wt1
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_144783
RefSeq Synonyms
NM_144783, BC148376,
Species
mouse
UniGene ID
Mm.389339

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.