mouse VRK1 Over-expression AAV

Name 
AAV-m-VRK1
Cat No 
AAV-276081
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Vrk1.

AAV-276081
AAV-m-VRK1

Ready-to-use AAV expressing Mouse Vrk1 (vaccinia related kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
51PK
Description (Vector)
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.
Gene ID
22367
Gene Name (Vector)
vaccinia related kinase 1
Gene Symbol
Vrk1
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_011705
RefSeq Synonyms
NM_011705, NM_001029844, NM_001029843, BC016676,
Species
mouse
UniGene ID
Mm.2981

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.