mouse UNC119 Over-expression AAV

Name 
AAV-m-UNC119
Cat No 
AAV-275629
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Unc119.

AAV-275629
AAV-m-UNC119

Ready-to-use AAV expressing Mouse Unc119 (unc-119 lipid binding chaperone). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D11Bhm52; HRG4; MRG4; Rg4; Rtg4; Unc119h
Description (Vector)
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.
Gene ID
22248
Gene Name (Vector)
unc-119 lipid binding chaperone
Gene Symbol
Unc119
ORF Size (aa)
723
RefSeq ID
NM_011676
RefSeq Synonyms
NM_011676, NM_001313988, NM_001313987, NM_001313986, NM_001313985, BC001990,
Species
mouse
UniGene ID
Mm.284811

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.