mouse U2AF2 Over-expression AAV
This is an AAV expressing Mouse U2af2.
AAV-275424
AAV-m-U2AF2
Ready-to-use AAV expressing Mouse U2af2 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
65kDa
Description (Vector)
Necessary for the splicing of pre-mRNA. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
Gene ID
22185
Gene Name (Vector)
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Gene Symbol
U2af2
ORF Size (aa)
921
ORF Size (bp)
921 bp
RefSeq ID
NM_133671
RefSeq Synonyms
NM_133671, NM_001205231, BC106134, BC043071, BC007487,
Species
mouse
UniGene ID
Mm.360389
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.