mouse TSEN15 Over-expression AAV
This is an AAV expressing Mouse Tsen15.
AAV-275129
AAV-m-TSEN15
Ready-to-use AAV expressing Mouse Tsen15 (tRNA splicing endonuclease subunit 15). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5730449L18Rik; AL023077; Sen15
Description (Vector)
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Gene ID
66637
Gene Name (Vector)
tRNA splicing endonuclease subunit 15
Gene Symbol
Tsen15
ORF Size (aa)
507
RefSeq ID
NM_025677
RefSeq Synonyms
NM_025677, BC145701, BC024342,
Species
mouse
UniGene ID
Mm.379120
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.