mouse TGM3 Over-expression AAV

Name 
AAV-m-TGM3
Cat No 
AAV-274119
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tgm3.

AAV-274119
AAV-m-TGM3

Ready-to-use AAV expressing Mouse Tgm3 (transglutaminase 3, E polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI893889; TG E; TG(E); TGase E; TGase-3; TGE; we
Description (Vector)
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Gene ID
21818
Gene Name (Vector)
transglutaminase 3, E polypeptide
Gene Symbol
Tgm3
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
RefSeq ID
NM_009374
RefSeq Synonyms
NM_009374, BC129891, BC129890,
Species
mouse
UniGene ID
Mm.2961

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.