mouse SYT1 Over-expression AAV

Name
AAV-m-SYT1

Cat No
AAV-273547

Availability
4-5 weeks

This is an AAV expressing Mouse Syt1.

AAV-273547

AAV-m-SYT1

Ready-to-use AAV expressing Mouse Syt1 (synaptotagmin I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW124717; G630098F17Rik; SytI

Description (Vector)

SYT1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

Gene ID

20979

Gene Name (Vector)

synaptotagmin I

Gene Symbol

Syt1

ORF Size (aa)

1266

ORF Size (bp)

1266 bp

RefSeq ID

NM_009306

RefSeq Synonyms

NM_009306, NM_001252342, NM_001252341, BC042519,

Species

mouse

UniGene ID

Mm.289702

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.