mouse SREBF2 Over-expression AAV

Name
AAV-m-SREBF2

Cat No
AAV-273128

Availability
4-5 weeks

This is an AAV expressing Mouse Srebf2.

AAV-273128

AAV-m-SREBF2

Ready-to-use AAV expressing Mouse Srebf2 (sterol regulatory element binding factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI608257; bHLHd2; lop13; nuc; SREBP-2; SREBP2; SREBP2gc

Description (Vector)

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.

Gene ID

20788

Gene Name (Vector)

sterol regulatory element binding factor 2

Gene Symbol

Srebf2

ORF Size (aa)

3393

ORF Size (bp)

3393 bp

RefSeq ID

NM_033218

RefSeq Synonyms

NM_033218, BC167259,

Species

mouse

UniGene ID

Mm.38016

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.