mouse SOCS4 Over-expression AAV

Name 
AAV-m-SOCS4
Cat No 
AAV-272834
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Socs4.

AAV-272834
AAV-m-SOCS4

Ready-to-use AAV expressing Mouse Socs4 (suppressor of cytokine signaling 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; Socs7
Description (Vector)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR.
Gene ID
67296
Gene Name (Vector)
suppressor of cytokine signaling 4
Gene Symbol
Socs4
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_080843
RefSeq Synonyms
NM_080843, BC117815, BC117814,
Species
mouse
UniGene ID
Mm.425886

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.