mouse SIGMAR1 Over-expression AAV

Name 
AAV-m-SIGMAR1
Cat No 
AAV-271989
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sigmar1.

AAV-271989
AAV-m-SIGMAR1

Ready-to-use AAV expressing Mouse Sigmar1 (sigma non-opioid intracellular receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Oprs1; Sig1R; sigma1R
Description (Vector)
Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
Gene ID
18391
Gene Name (Vector)
sigma non-opioid intracellular receptor 1
Gene Symbol
Sigmar1
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_011014
RefSeq Synonyms
NM_011014, NM_001286605, NM_001286551, NM_001286542, NM_001286541, NM_001286540, NM_001286539, NM_001286538, BC019930, BC002000,
Species
mouse
UniGene ID
Mm.425181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.