mouse SFRP1 Over-expression AAV

Name 
AAV-m-SFRP1
Cat No 
AAV-271801
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sfrp1.

AAV-271801
AAV-m-SFRP1

Ready-to-use AAV expressing Mouse Sfrp1 (secreted frizzled-related protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2210415K03Rik; AW011917; AW107218; AW742929; sFRP-1
Description (Vector)
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Gene ID
20377
Gene Name (Vector)
secreted frizzled-related protein 1
Gene Symbol
Sfrp1
ORF Size (aa)
945
RefSeq ID
NM_013834
RefSeq Synonyms
NM_013834, BC094662, BC024495,
Species
mouse
UniGene ID
Mm.281691

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.