mouse SARM1 Over-expression AAV

Name 
AAV-m-SARM1
Cat No 
AAV-271364
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sarm1.

AAV-271364
AAV-m-SARM1

Ready-to-use AAV expressing Mouse Sarm1 (sterile alpha and HEAT/Armadillo motif containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A830091I15Rik; C78606; MyD885; Sarm
Description (Vector)
Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.
Gene ID
237868
Gene Name (Vector)
sterile alpha and HEAT/Armadillo motif containing 1
Gene Symbol
Sarm1
ORF Size (aa)
2175
ORF Size (bp)
2175 bp
RefSeq ID
NM_172795
RefSeq Synonyms
NM_172795, NM_001168521, BC080850, BC058534,
Species
mouse
UniGene ID
Mm.210332

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.