mouse RSPO1 Over-expression AAV

Name 
AAV-m-RSPO1
Cat No 
AAV-271184
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rspo1.

AAV-271184
AAV-m-RSPO1

Ready-to-use AAV expressing Mouse Rspo1 (R-spondin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
R-spondin; Rspondin
Description (Vector)
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
Gene ID
192199
Gene Name (Vector)
R-spondin 1
Gene Symbol
Rspo1
ORF Size (aa)
798
ORF Size (bp)
798 bp
RefSeq ID
NM_138683
RefSeq Synonyms
NM_138683, BC138833, BC138831,
Species
mouse
UniGene ID
Mm.42202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.