mouse RBPJ Over-expression AAV

Name 
AAV-m-RBPJ
Cat No 
AAV-270295
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rbpj.

AAV-270295
AAV-m-RBPJ

Ready-to-use AAV expressing Mouse Rbpj (recombination signal binding protein for immunoglobulin kappa J region). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI843960; CBF1; Igkjrb; Igkrsbp; RBP-J; RBP-J kappa; RBP-Jkappa; RBPjk; Rbpsuh
Description (Vector)
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
Gene ID
19664
Gene Name (Vector)
recombination signal binding protein for immunoglobulin kappa J region
Gene Symbol
Rbpj
ORF Size (aa)
1464
ORF Size (bp)
1464 bp
RefSeq ID
NM_009035
RefSeq Synonyms
NM_009035, NM_001277116, NM_001080928, NM_001080927, BC051387,
Species
mouse
UniGene ID
Mm.209292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.