mouse RASSF5 Over-expression AAV

Name 
AAV-m-RASSF5
Cat No 
AAV-270201
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rassf5.

AAV-270201
AAV-m-RASSF5

Ready-to-use AAV expressing Mouse Rassf5 (Ras association (RalGDS/AF-6) domain family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1300019G20Rik; Maxp1; Nore1; Nore1A; Nore1B; Rapl
Description (Vector)
Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS1 and KRAS induced apoptosis.
Gene ID
54354
Gene Name (Vector)
Ras association (RalGDS/AF-6) domain family member 5
Gene Symbol
Rassf5
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_018750
RefSeq Synonyms
NM_018750, NM_001313731, NM_001311094, BC089605,
Species
mouse
UniGene ID
Mm.248291

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.