mouse RASGRP1 Over-expression AAV

Name 
AAV-m-RASGRP1
Cat No 
AAV-270173
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Rasgrp1.

AAV-270173
AAV-m-RASGRP1

Ready-to-use AAV expressing Mouse Rasgrp1 (RAS guanyl releasing protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Rasgrp
Description (Vector)
Functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Couples T-lymphocytes and B-lymphocytes antigen receptors to the activation of Ras. Hence, regulates T-cells and B-cells development, homeostasis and differentiation. Functions also in FcERI-evoked degranulation and cytokine secretion by mast cells, regulating allergic responses. May also function in other cell types differentiation.
Gene ID
19419
Gene Name (Vector)
RAS guanyl releasing protein 1
Gene Symbol
Rasgrp1
ORF Size (aa)
2388
ORF Size (bp)
2388 bp
RefSeq ID
NM_011246
RefSeq Synonyms
NM_011246, BC057341, BC057120,
Species
mouse
UniGene ID
Mm.42150

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.