mouse RANBP3 Over-expression AAV

Name 
AAV-m-RANBP3
Cat No 
AAV-270113
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ranbp3.

AAV-270113
AAV-m-RANBP3

Ready-to-use AAV expressing Mouse Ranbp3 (RAN binding protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610024N24Rik; AA408221
Description (Vector)
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Gene ID
71810
Gene Name (Vector)
RAN binding protein 3
Gene Symbol
Ranbp3
ORF Size (aa)
1476
ORF Size (bp)
1476 bp
RefSeq ID
NM_027933
RefSeq Synonyms
NM_027933, NM_001252467, NM_001252466, BC145894, BC145892,
Species
mouse
UniGene ID
Mm.469805

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.