mouse PLEKHG6 Over-expression AAV

Name 
AAV-m-PLEKHG6
Cat No 
AAV-268868
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Plekhg6.

AAV-268868
AAV-m-PLEKHG6

Ready-to-use AAV expressing Mouse Plekhg6 (pleckstrin homology domain containing, family G (with RhoGef domain) member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BC026778; Gm155
Description (Vector)
Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Gene ID
213522
Gene Name (Vector)
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Gene Symbol
Plekhg6
ORF Size (aa)
2364
ORF Size (bp)
2364 bp
RefSeq ID
NM_198604
RefSeq Synonyms
NM_198604, BC026778,
Species
mouse
UniGene ID
Mm.333396

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.