mouse PLEKHF1 Over-expression AAV

Name 
AAV-m-PLEKHF1
Cat No 
AAV-268855
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Plekhf1.

AAV-268855
AAV-m-PLEKHF1

Ready-to-use AAV expressing Mouse Plekhf1 (pleckstrin homology domain containing, family F (with FYVE domain) member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1810013P09Rik; APPD; LAPF; PHAFIN1; ZFYVE15
Description (Vector)
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Gene ID
72287
Gene Name (Vector)
pleckstrin homology domain containing, family F (with FYVE domain) member 1
Gene Symbol
Plekhf1
ORF Size (aa)
840
RefSeq ID
NM_024413
RefSeq Synonyms
NM_024413, BC002120,
Species
mouse
UniGene ID
Mm.333798

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.