mouse PHLDA3 Over-expression AAV

Name 
AAV-m-PHLDA3
Cat No 
AAV-268560
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Phlda3.

AAV-268560
AAV-m-PHLDA3

Ready-to-use AAV expressing Mouse Phlda3 (pleckstrin homology like domain, family A, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Tih1
Description (Vector)
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor.
Gene ID
27280
Gene Name (Vector)
pleckstrin homology like domain, family A, member 3
Gene Symbol
Phlda3
ORF Size (aa)
378
RefSeq ID
NM_013750
RefSeq Synonyms
NM_013750, BC023408,
Species
mouse
UniGene ID
Mm.34346

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.