mouse PARP3 Over-expression AAV

Name 
AAV-m-PARP3
Cat No 
AAV-268081
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Parp3.

AAV-268081
AAV-m-PARP3

Ready-to-use AAV expressing Mouse Parp3 (poly (ADP-ribose) polymerase family, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A930002C11Rik; Adprt3; Adprtl3; AW990611; pADPRT-3; PARP-3
Description (Vector)
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Gene ID
235587
Gene Name (Vector)
poly (ADP-ribose) polymerase family, member 3
Gene Symbol
Parp3
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
RefSeq ID
NM_145619
RefSeq Synonyms
NM_145619, NM_001311150, BC058754, BC014870,
Species
mouse
UniGene ID
Mm.273659

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.