mouse NUP85 Over-expression AAV

Name 
AAV-m-NUP85
Cat No 
AAV-266230
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nup85.

AAV-266230
AAV-m-NUP85

Ready-to-use AAV expressing Mouse Nup85 (nucleoporin 85). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
frount; Pcnt1
Description (Vector)
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.
Gene ID
445007
Gene Name (Vector)
nucleoporin 85
Gene Symbol
Nup85
ORF Size (aa)
1971
ORF Size (bp)
1971 bp
RefSeq ID
NM_001002929
RefSeq Synonyms
NM_001002929, BC079856,
Species
mouse
UniGene ID
Mm.4379

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.