mouse NRG1 Over-expression AAV

Name 
AAV-m-NRG1
Cat No 
AAV-266077
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nrg1.

AAV-266077
AAV-m-NRG1

Ready-to-use AAV expressing Mouse Nrg1 (neuregulin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6030402G23Rik; ARIA; D230005F13Rik; GGF; GGFII; Hgl; HRG; HRGalpha; NDF; SMDF
Description (Vector)
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Gene ID
211323
Gene Name (Vector)
neuregulin 1
Gene Symbol
Nrg1
ORF Size (aa)
2103
ORF Size (bp)
2103 bp
RefSeq ID
NM_178591
RefSeq Synonyms
NM_178591, BC160344, BC151113,
Species
mouse
UniGene ID
Mm.460675

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.