mouse NR0B2 Over-expression AAV

Name 
AAV-m-NR0B2
Cat No 
AAV-266031
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nr0b2.

AAV-266031
AAV-m-NR0B2

Ready-to-use AAV expressing Mouse Nr0b2 (nuclear receptor subfamily 0, group B, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SHP; SHP-1; Shp1
Description (Vector)
Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.
Gene ID
23957
Gene Name (Vector)
nuclear receptor subfamily 0, group B, member 2
Gene Symbol
Nr0b2
ORF Size (aa)
783
ORF Size (bp)
783 bp
RefSeq ID
NM_011850
RefSeq Synonyms
NM_011850, BC019540,
Species
mouse
UniGene ID
Mm.346759

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.