mouse NPC1L1 Over-expression AAV
This is an AAV expressing Mouse Npc1l1.
AAV-265970
AAV-m-NPC1L1
Ready-to-use AAV expressing Mouse Npc1l1 (NPC1-like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9130221N23Rik; Gm243
Description (Vector)
Play a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorbtion. Lack of activity leads to multiple lipid transport defects. The protein may have a function in the transport of multiple lipids and their homeostasis, and may play a critical role in regulating lipid metabolism.
Gene ID
237636
Gene Name (Vector)
NPC1-like 1
Gene Symbol
Npc1l1
ORF Size (aa)
2184
ORF Size (bp)
2184 bp
RefSeq ID
NM_207242
RefSeq Synonyms
NM_207242, BC131789,
Species
mouse
UniGene ID
Mm.212492
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.