mouse NOTO Over-expression AAV

Name 
AAV-m-NOTO
Cat No 
AAV-265948
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Noto.

AAV-265948
AAV-m-NOTO

Ready-to-use AAV expressing Mouse Noto (notochord homeobox). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Flh; MmNot; Not; tc
Description (Vector)
Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate (By similarity).
Gene ID
384452
Gene Name (Vector)
notochord homeobox
Gene Symbol
Noto
ORF Size (aa)
723
RefSeq ID
NM_001007472
RefSeq Synonyms
NM_001007472, BC139155, BC139154,
Species
mouse
UniGene ID
Mm.347883

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.