mouse NOD1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-265907
Availability:
3-5 weeks
Name:
AAV-m-NOD1
This is an AAV expressing Mouse Nod1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Nod1
- Gene Name
- nucleotide-binding oligomerization domain containing 1
- Gene ID
- 107607
- Gene Synonyms
- C230079P11; Card4; F830007N14Rik; Nlrc1
- ORF Size
- 2862 bp
- RefSeq#
- BC042670
- Gene Description
- Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathways activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB.
- UniGene ID
- Mm.28498
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