mouse NKX3-1 Over-expression AAV

Name 
AAV-m-NKX3-1
Cat No 
AAV-265823
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nkx3-1.

AAV-265823
AAV-m-NKX3-1

Ready-to-use AAV expressing Mouse Nkx3-1 (NK-3 transcription factor, locus 1 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bagpipe; Bax; Nkx-3.1; NKX3.1; NKX3A
Description (Vector)
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Gene ID
18095
Gene Name (Vector)
NK-3 transcription factor, locus 1 (Drosophila)
Gene Symbol
Nkx3-1
ORF Size (aa)
714
RefSeq ID
NM_010921
RefSeq Synonyms
NM_010921, BC132427, BC132401,
Species
mouse
UniGene ID
Mm.3520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.