mouse NIT1 Over-expression AAV

Name 
AAV-m-NIT1
Cat No 
AAV-265791
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nit1.

AAV-265791
AAV-m-NIT1

Ready-to-use AAV expressing Mouse Nit1 (nitrilase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI255805; ESTM30; W57327
Description (Vector)
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity).
Gene ID
27045
Gene Name (Vector)
nitrilase 1
Gene Symbol
Nit1
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_012049
RefSeq Synonyms
NM_012049, NM_001242580, BC021634,
Species
mouse
UniGene ID
Mm.12915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.