mouse NFE2 Over-expression AAV

Name 
AAV-m-NFE2
Cat No 
AAV-265708
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Nfe2.

AAV-265708
AAV-m-NFE2

Ready-to-use AAV expressing Mouse Nfe2 (nuclear factor, erythroid derived 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NF-E2; NF-E2/P45; p45; p45nf-e2; p45NFE2
Description (Vector)
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Gene ID
18022
Gene Name (Vector)
nuclear factor, erythroid derived 2
Gene Symbol
Nfe2
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_008685
RefSeq Synonyms
NM_008685, NM_001302343, NM_001302341, NM_001302340, NM_001302339, NM_001302338, BC062171,
Species
mouse
UniGene ID
Mm.457989

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.