mouse NEUROD2 Over-expression AAV
This is an AAV expressing Mouse Neurod2.
AAV-265691
AAV-m-NEUROD2
Ready-to-use AAV expressing Mouse Neurod2 (neurogenic differentiation 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHa1; Ndrf
Description (Vector)
Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter (By similarity).
Gene ID
18013
Gene Name (Vector)
neurogenic differentiation 2
Gene Symbol
Neurod2
ORF Size (aa)
1152
RefSeq ID
NM_010895
RefSeq Synonyms
NM_010895, BC058965,
Species
mouse
UniGene ID
Mm.4814
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.