mouse NDUFA13 Over-expression AAV

Name 
AAV-m-NDUFA13
Cat No 
AAV-265563
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ndufa13.

AAV-265563
AAV-m-NDUFA13

Ready-to-use AAV expressing Mouse Ndufa13 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2700054G14Rik; AU022060; CDA016; CGI-39; GRIM-19; Grim19
Description (Vector)
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
Gene ID
67184
Gene Name (Vector)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
Gene Symbol
Ndufa13
ORF Size (aa)
435
ORF Size (bp)
435 bp
RefSeq ID
NM_023312
RefSeq Synonyms
NM_023312, BC055435, BC037149, BC034899,
Species
mouse
UniGene ID
Mm.21162

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.