mouse NDST1 Over-expression AAV

Name 
AAV-m-NDST1
Cat No 
AAV-265553
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ndst1.

AAV-265553
AAV-m-NDST1

Ready-to-use AAV expressing Mouse Ndst1 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1200015G06Rik; b2b2230Clo; Hsst; NDST-1
Description (Vector)
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
Gene ID
15531
Gene Name (Vector)
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Gene Symbol
Ndst1
ORF Size (aa)
2649
ORF Size (bp)
2649 bp
RefSeq ID
NM_008306
RefSeq Synonyms
NM_008306, BC079561, BC066098,
Species
mouse
UniGene ID
Mm.181862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.