mouse NCK1 Over-expression AAV
This is an AAV expressing Mouse Nck1.
AAV-265508
AAV-m-NCK1
Ready-to-use AAV expressing Mouse Nck1 (non-catalytic region of tyrosine kinase adaptor protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330586M15Rik; D230010O13Rik; Nck; Nck-1
Description (Vector)
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Gene ID
17973
Gene Name (Vector)
non-catalytic region of tyrosine kinase adaptor protein 1
Gene Symbol
Nck1
ORF Size (aa)
1134
ORF Size (bp)
1134 bp
RefSeq ID
NM_010878
RefSeq Synonyms
NM_010878, NM_001324530, BC002015,
Species
mouse
UniGene ID
Mm.471648
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.