mouse MMP17 Over-expression AAV

Name
AAV-m-MMP17

Cat No
AAV-264724

Availability
4-5 weeks

This is an AAV expressing Mouse Mmp17.

AAV-264724

AAV-m-MMP17

Ready-to-use AAV expressing Mouse Mmp17 (matrix metallopeptidase 17). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MT4-MMP; MT4MMP; MTMMP4

Description (Vector)

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Gene ID

23948

Gene Name (Vector)

matrix metallopeptidase 17

Gene Symbol

Mmp17

ORF Size (aa)

1737

ORF Size (bp)

1737 bp

RefSeq ID

NM_011846

RefSeq Synonyms

NM_011846, BC051917,

Species

mouse

UniGene ID

Mm.42047

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.