mouse MITF Over-expression AAV

Name 
AAV-m-MITF
Cat No 
AAV-264666
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Mitf.

AAV-264666
AAV-m-MITF

Ready-to-use AAV expressing Mouse Mitf (microphthalmia-associated transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BCC2; Bhlhe32; bw; Gsfbcc2; mi; vit; Vitiligo; Wh
Description (Vector)
Transcription factor for tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) that plays a key role in melanocyte development. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Gene ID
17342
Gene Name (Vector)
microphthalmia-associated transcription factor
Gene Symbol
Mitf
ORF Size (aa)
1260
RefSeq ID
NM_008601
RefSeq Synonyms
NM_008601, NM_001178049, NM_001113198, BC108977, BC108976,
Species
mouse
UniGene ID
Mm.454504

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.