mouse MED8 Over-expression AAV

Name 
AAV-m-MED8
Cat No 
AAV-264466
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Med8.

AAV-264466
AAV-m-MED8

Ready-to-use AAV expressing Mouse Med8 (mediator complex subunit 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2210021A15Rik; AB041805; ARC32
Description (Vector)
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
Gene ID
80509
Gene Name (Vector)
mediator complex subunit 8
Gene Symbol
Med8
ORF Size (aa)
807
ORF Size (bp)
807 bp
RefSeq ID
NM_020000
RefSeq Synonyms
NM_173719, NM_020000, NM_001290688, BC021870,
Species
mouse
UniGene ID
Mm.259567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.