mouse MAP3K11 Over-expression AAV
This is an AAV expressing Mouse Map3k11.
AAV-264180
AAV-m-MAP3K11
Ready-to-use AAV expressing Mouse Map3k11 (mitogen-activated protein kinase kinase kinase 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610017K16Rik; Mlk3; PTK1; SPRK
Description (Vector)
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Gene ID
26403
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 11
Gene Symbol
Map3k11
ORF Size (aa)
2553
ORF Size (bp)
2553 bp
RefSeq ID
NM_022012
RefSeq Synonyms
NM_022012, BC095963, BC047152,
Species
mouse
UniGene ID
Mm.185026
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.