mouse LRAT Over-expression AAV

Name 
AAV-m-LRAT
Cat No 
AAV-263790
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lrat.

AAV-263790
AAV-m-LRAT

Ready-to-use AAV expressing Mouse Lrat (lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1300010A18Rik; AI449251
Description (Vector)
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters. Retinyl esters are storage forms of vitamin A. LRAT plays a critical role in vision. It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments.
Gene ID
79235
Gene Name (Vector)
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Gene Symbol
Lrat
ORF Size (aa)
696
RefSeq ID
NM_023624
RefSeq Synonyms
NM_023624, BC141378, BC141375,
Species
mouse
UniGene ID
Mm.33921

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.