mouse LNX1 Over-expression AAV

Name 
AAV-m-LNX1
Cat No 
AAV-263547
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Lnx1.

AAV-263547
AAV-m-LNX1

Ready-to-use AAV expressing Mouse Lnx1 (ligand of numb-protein X 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Lnx
Description (Vector)
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity)|Function: Isoform 2 provides an endocytic scaffold for IGSF5/JAM4 (By similarity).
Gene ID
16924
Gene Name (Vector)
ligand of numb-protein X 1
Gene Symbol
Lnx1
ORF Size (aa)
1887
ORF Size (bp)
1887 bp
RefSeq ID
NM_010727
RefSeq Synonyms
NM_010727, NM_001159580, NM_001159579, NM_001159578, NM_001159577, BC139771,
Species
mouse
UniGene ID
Mm.440403

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.