mouse LIG4 Over-expression AAV
This is an AAV expressing Mouse Lig4.
AAV-263448
AAV-m-LIG4
Ready-to-use AAV expressing Mouse Lig4 (ligase IV, DNA, ATP-dependent). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5830471N16Rik; tiny
Description (Vector)
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Gene ID
319583
Gene Name (Vector)
ligase IV, DNA, ATP-dependent
Gene Symbol
Lig4
ORF Size (aa)
2733
ORF Size (bp)
2733 bp
RefSeq ID
NM_176953
RefSeq Synonyms
NM_176953, BC141417,
Species
mouse
UniGene ID
Mm.80584
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.