mouse KDM4A Over-expression AAV

Name 
AAV-m-KDM4A
Cat No 
AAV-262763
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Kdm4a.

AAV-262763
AAV-m-KDM4A

Ready-to-use AAV expressing Mouse Kdm4a (lysine (K)-specific demethylase 4A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D4Ertd222e; JHDM3A; Jmjd2; Jmjd2a; mKIAA0677
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Gene ID
230674
Gene Name (Vector)
lysine (K)-specific demethylase 4A
Gene Symbol
Kdm4a
ORF Size (aa)
3102
ORF Size (bp)
3102 bp
RefSeq ID
NM_172382
RefSeq Synonyms
NM_172382, NM_001161823, BC028866,
Species
mouse
UniGene ID
Mm.234234

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.