mouse JTV1 Over-expression AAV

Name 
AAV-m-JTV1
Cat No 
AAV-262543
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Aimp2.

AAV-262543
AAV-m-JTV1

Ready-to-use AAV expressing Mouse Aimp2 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA407136; AA407225; Aimp2(p38); Jtv1
Description (Vector)
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Gene ID
231872
Gene Name (Vector)
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Gene Symbol
Aimp2
ORF Size (aa)
963
RefSeq ID
NM_146165
RefSeq Synonyms
NM_146165, NM_001172146, BC026972, BC026958, BC024480, BC024410,
Species
mouse
UniGene ID
Mm.200499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.