mouse JTV1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-262542
Availability:
3-5 weeks
Name:
AAV-m-JTV1
This is an AAV expressing Mouse Aimp2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Aimp2
- Gene Name
- aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
- Gene ID
- 231872
- Gene Synonyms
- AA407136; AA407225; Aimp2(p38); Jtv1
- ORF Size
- 843 bp
- RefSeq#
- BC024480
- Gene Description
- Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
- UniGene ID
- Mm.200499
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