mouse HSD17B6 Over-expression AAV

Name 
AAV-m-HSD17B6
Cat No 
AAV-261704
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Hsd17b6.

AAV-261704
AAV-m-HSD17B6

Ready-to-use AAV expressing Mouse Hsd17b6 (hydroxysteroid (17-beta) dehydrogenase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
17betaHSD9; Hsd17b9; Rdh8
Description (Vector)
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Gene ID
27400
Gene Name (Vector)
hydroxysteroid (17-beta) dehydrogenase 6
Gene Symbol
Hsd17b6
ORF Size (aa)
954
ORF Size (bp)
954 bp
RefSeq ID
NM_013786
RefSeq Synonyms
NM_013786, BC021836,
Species
mouse
UniGene ID
Mm.26719

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.