mouse GZMM Over-expression AAV

Name 
AAV-m-GZMM
Cat No 
AAV-260987
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Gzmm.

AAV-260987
AAV-m-GZMM

Ready-to-use AAV expressing Mouse Gzmm (granzyme M (lymphocyte met-ase 1)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Lmet1; MMET-1
Description (Vector)
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
Gene ID
16904
Gene Name (Vector)
granzyme M (lymphocyte met-ase 1)
Gene Symbol
Gzmm
ORF Size (aa)
792
ORF Size (bp)
792 bp
RefSeq ID
NM_008504
RefSeq Synonyms
NM_008504, NM_001302499, NM_001302485, BC145578, BC139218, BC139217,
Species
mouse
UniGene ID
Mm.378960

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.