mouse GUCA1B Over-expression AAV

Name
AAV-m-GUCA1B

Cat No
AAV-260927

Availability
4-5 weeks

This is an AAV expressing Mouse Guca1b.

AAV-260927

AAV-m-GUCA1B

Ready-to-use AAV expressing Mouse Guca1b (guanylate cyclase activator 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BC018258; GCAP2

Description (Vector)

Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low, and GC1 and GC2 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure.

Gene ID

107477

Gene Name (Vector)

guanylate cyclase activator 1B

Gene Symbol

Guca1b

ORF Size (aa)

606

RefSeq ID

NM_146079

RefSeq Synonyms

NM_146079, BC034595, BC034331, BC033383, BC033380, BC033358, BC031916, BC031367, BC029661, BC029017, BC018480, BC018258,

Species

mouse

UniGene ID

Mm.59151

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.